Zvinodhaka zveAbuse Screening (DOAS)

Zvinodhaka zveAbuse screening (DOAS)inogona kuodha mune akati wandei mamiriro anosanganisira:

• Kuongorora kutevedzerwa kwemishonga inotsiva (semuenzaniso methadone) muvarwere vanozivikanwa kuti vanoshandisa zvinhu zvisiri pamutemo.

Kuongororwa kwezvinodhaka zvekushungurudzwakazhinji zvinosanganisira kuongorora weti yemhando yemishonga yakawanda.Izvo zvinofanirwa kucherechedzwa, zvisinei, kuti imwe chete weti yemushonga bvunzo inongoona ichangoburwa kushandiswa kwezvinodhaka uye haina kusiyanisa kushandiswa kwechikafu kubva mukusingaperi kushandiswa kwezvinodhaka.Iyo yekupedzisira inoda kutevedzana kuongororwa kwezvinodhaka uye kuongororwa kwekiriniki.Zvakare, kuongororwa weti hakutaridzi chiyero chekukanganisa, chiyero chemushonga wakatorwa kana nguva chaiyo yekushandiswa.

Pachinyakare, DOAS inoitwa kuburikidza neyekutanga immunoassay skrini yekirasi yemishonga (semuenzaniso maopiates).Sezvo iyi iri nzira isiri-yakananga yekuongorora, chero mibairo yakanaka inofanirwa kusimbiswa neyakajeka technqiue, kazhinji inosanganisira imwe mhando yekuparadzanisa chromatographic.Nzira yekusimbisa inogamuchirwa zvakanyanya ndeyeGC-MS.

Kuti udzivise kuongororwa kwekurebesa kwekusimbisa uye nyonganiso yekuongorora, Dhipatimendi reToxicology paHeartlands Hospital rinoshandisa mishonga yakanangwa yekuzivikanwa nekushungurudzwa ne liquid chromatography tandem mass spectrometry (LC-MS/MS).Iyi tekinoroji ine mukana wakasiyana weashoma sampuli yekugadzirira nguva pamwe nekukwanisa kuita kuongorora uye kuzivikanwa kwemhando yekomboni panguva imwe chete.Mhedzisiro yakanaka inomiririra kuwanda kwemishonga iri pamusoro peEuropean Workplace Testing Thresholds.Mishonga inotevera inoongororwa:

Opiates - Morphine, Codeine, Dihydrocodeine & 6-monoacetyl morphine (6MAM)

Opioids - Methadone uye metabolite (EDDP), Buprenorphine uye metabolite (norbuprenorphine)

Amphetamines - Amphetamine, Methamphetamine, MDA, MDMA & MDEA

Benzodiazepines - Diazepam uye metabolite (nordiazepam), oxazepam, temazepam, lorazepam, nitrazepam & midazolam

Mugadziri wemishonga - Benzylpiperazine (BZP), MDPV (bath salts), 4-Methylethcathinone (4-MEC, NRG), 4-Methylmethcathinone (Mephedrone, Meow Meow)

Mimwe mishonga - Cocaine uye metabolite (benzoylecgonine), Ketamine, Cannabis metabolite (11-nor-9-carboxy-tetrahydrocannabinol)

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